Katarzyna Małolepsza-Jarmołowska

Wpływ PEG-200 na uwalnianie metronidazolu z żeli zawierających kompleks kwasu mlekowego z Eudragitem E-100

PEG-200 influence on metronidazole release from gels containing lactic acid complexed with Eudragit-E-100. Metronidazole release form methylcellulose gels containing lactic acid complexed with Eudragit E-100 in 1:1, 2: 1, 3:1 and 4:1 molar ratio was shown to be differentiated. Half-release time is from 29 to 64 hours. This will enable selection of a preparation with optimum metronidazole release rate providing its antibacterial level at the site of application.