Katarzyna Sosnowska, Katarzyna Winnicka
Ocena trwałości klotrimazolu w hydrożelach wykonanych na bazie Carbopolu 980 oraz hydroksyetylocelulozy
Evaluation of the stability of clotrimazole in hydrogels made on Carbopol 980 and hydroxyethylcellulose base
There is no clotrimazole in hydrogels on polish pharmaceutical market therefore hydrogels with clotrimazole made on Carbopol 980 and hydroksyethylcellulose base were prepared and examined. All the formulations retain minimum 97% of the initial clotrimazole concentration after four week of storage at room temperature. Viscosity and pH of all tested formulations did not significantly change over 28 days.
Keywords: hydrogels, clotrimazole, HPLC