W. Sawicki, P. Łepek, M. Kleina
Otoczki na tabletkach i peletkach - budowa, funkcja, mechanizm i metody powlekania
Film coating for tablets and pellets - structure, function, mechanism and methods of coating
Coating is one of the most important formative stage of solid dosage forms: granulates, tablets, pellets, minitablets or microcapsules. There are two types of coated forms: dragees and tablets coated with polymer - lm. Solubility of polymer - lm determines its function. Film coating protects API before external environment, facilitates administration and masks unpleasant taste (sugar coated and water soluble polymer coated forms) and makes modi- cated release e- ect (enteric and insoluble polymer coated forms). The most common method of preparation of - lm coating is spraying the - lm coating mixture over the cores. There are several types of coating processes, widely used are: coating in the perforated drum or bed - uid coating. Spray dryer coating or with rotating nozzle are rarely used.
Keywords: polymer lm coating, coating, structure and function of lm coating, methods of coating.