The term „chemsex” refers to use of illicit psychoactive drugs, before or during sex with the intention to facilitate, initiate, prolong, sustain and intensify the encounter. Chemsex is increasingly popular among gay, bisexual, and other men who have sex with men. Certain drugs have been associated with chemsex behavior, including mephedrone, methamphetamine and γ-hydroxybutyrate (GHB)/γ- butyrolactone (GBL); ketamine, cocaine and ecstasy are less popular. In addition, erectile enhancers and alkyl nitrites („poppers”) are used to increase sexual activity and to ease an anal sex, respectively. Accumulating epidemiological data indicate that “chemsex” is associated with a risky sexual behavior leading to increased risk of contracting HIV and other sexually transmitted diseases. In addition, prolonged use of psychoactive substances of abuse can result in the development of addition, psychiatric disturbances/illness, loss of job, homeless, and even crime activity.

Keywords: methamphetamine, mephedrone, GHB, HIV, sexual activity.